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Acute toxicity |
LD50 Oral - Rat - female - 1.690 mg/kg (OECD Test Guideline 401) LC50 Inhalation - Mouse - 4 h - 10,9 mg/l - vapor Remarks: Lungs, Thorax, or Respiration:Acute pulmonary edema. Liver:Other changes. Kidney, Ureter, Bladder:Other changes. (RTECS) LD50 Dermal - Rabbit - female - 2.460 mg/kg (OECD Test Guideline 402) Remarks: Behavioral:Somnolence (general depressed activity). Behavioral:Convulsions or effect on seizure threshold. Lungs, Thorax, or Respiration:Dyspnea. |
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Skin corrosion/irritation |
Skin - Rabbit Result: Skin irritation - 4 h (OECD Test Guideline 404) |
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Serious eye damage/eye irritation |
Remarks: Causes serious eye damage. |
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Respiratory or skin sensitization |
Local lymph node assay (LLNA) - Mouse Result: negative (OECD Test Guideline 429) |
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Toxic Effects on Human |
May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer). |
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Carcinogenicity |
No data available |
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Germ cell mutagenicity |
Test Type: Ames test Test system: S. typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Test Type: Micronucleus test Species: Mouse Method: OECD Test Guideline 474 Result: negative |
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Reproductive toxicity |
No data available |
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Specific target organ toxicity - single exposure |
May cause respiratory irritation. |
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Special Remarks on other Toxi Effects on Humans |
Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomes evident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tract irritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May cause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential Health Effects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolonged exposure by inhalation may affect respiration and metabolism. |
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Endocrine disrupting properties |
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: UE0350000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. After absorption: Tiredness narcosis Other dangerous properties can not be excluded. Handle in accordance with good industrial hygiene and safety practice. |